Acyclovir
Generic Drugs:
Acyclovir / Acyclovir
Branded Medicine:
Acifar, Clinovir, Clopes, Danovir, Herax, Herpiclof, Licovir, Lovires, Molavir, Palovir, Poviral, Scanovir, Viral, Vircovir, Vireth, Virules, Zoter, Zovirax, Zyclorax
COMPOSITION
Acyclovir 200 mg: Each tablet contains 200 mg of Acyclovir.
Acyclovir 400 mg: Each tablet contains Acyclovir 400 mg.
PHARMACOLOGY (HOW TO WORK DRUGS)
Acyclovir (Acyclovir) is an acyclic purine nucleoside analog which is active against the Herpes simplex virus, Varicella zoster, Epstein-Barr and Cytomegalovirus.
In cells, acyclovir undergoes phosphorylation into an active form of acyclovir triphosphate which works to inhibit herpes simplex DNA polymerase virus and viral DNA replication, thus preventing viral DNA synthesis without affecting normal cell processes.
INDICATION
Treatment of the herpes simplex virus in the skin and mucous membranes, including initial and recurrent genital herpes.
Treatment of herpes zoster and varicella infections.
CONTRAINDICATIONS
Acyclovir should not be given to people who are hypersensitive or allergic to acyclovir antibiotics.
DOSAGE AND RULES FOR USE
Genital herpes infection
Initial genital herpes infections in adults: Acyclovir 200 mg 5 times a day every 4 hours, for 5-10 days. Children under 2 years: 1/2 adult dose. For patients with "immunocompromised" or abnormal absorption in the intestine the dosage can be increased to 400 mg, or alternatively given treatment intravenously. Treatment should be started as early as possible, for recurrence, preferably in the period beginning with the first lesion.
Treatment of suppression of recurrent genital herpes infections: Acyclovir 400 mg 2 times a day or 200 mg 2-5 times a day, for 12 months.
Intermittent treatment of recurrent genital herpes infections: Acyclovir 200 mg 5 times a day every 4 hours, for 5 days.
Shingles and varicella infections
Adults: Acyclovir 800 mg 5 times a day every 4 hours, for 7-10 days.
Children 2 - 12 years: Acyclovir 400 - 800 mg 4 times a day, for 5 times.
Children under 2 years: Acyclovir 200 mg or 20 mg / kg BB 4 times a day, for 5 days.
Treatment must begin as early as possible and at the onset of symptoms of infection.
Patients who experience kidney function disorders need dose adjustments.
Some sufferers may experience a "break through" infection with a total dose of 800 mg a day. Treatment should be stopped periodically at intervals of 6 - 12 months with a view to observing possible changes in history.
SIDE EFFECTS
Side effects of Acyclovir that can occur: skin ulcers and digestive disorders such as nausea, vomiting, diarrhea and abdominal pain.
WARNING AND CAUTION
Acyclovir should not be used during pregnancy unless the benefits obtained far outweigh the risks to both the mother and the fetus.
Beware of giving to women who are breastfeeding.
DRUG INTERACTIONS
Probenecid increases the half-life and aciclovir AUC.
PACKAGING
Acyclovir 200 mg, tablet, box, fill 10 strips @ 10 capsules.
Acyclovir 400 mg, tablet, box, fill 10 strips @ 10 capsules.
Generic Drugs:
Acyclovir / Acyclovir
 |
| Acyclovir |
Branded Medicine:
Acifar, Clinovir, Clopes, Danovir, Herax, Herpiclof, Licovir, Lovires, Molavir, Palovir, Poviral, Scanovir, Viral, Vircovir, Vireth, Virules, Zoter, Zovirax, Zyclorax
COMPOSITION
Acyclovir 200 mg: Each tablet contains 200 mg of Acyclovir.
Acyclovir 400 mg: Each tablet contains Acyclovir 400 mg.
PHARMACOLOGY (HOW TO WORK DRUGS)
Acyclovir (Acyclovir) is an acyclic purine nucleoside analog which is active against the Herpes simplex virus, Varicella zoster, Epstein-Barr and Cytomegalovirus.
In cells, acyclovir undergoes phosphorylation into an active form of acyclovir triphosphate which works to inhibit herpes simplex DNA polymerase virus and viral DNA replication, thus preventing viral DNA synthesis without affecting normal cell processes.
INDICATION
Treatment of the herpes simplex virus in the skin and mucous membranes, including initial and recurrent genital herpes.
Treatment of herpes zoster and varicella infections.
CONTRAINDICATIONS
Acyclovir should not be given to people who are hypersensitive or allergic to acyclovir antibiotics.
DOSAGE AND RULES FOR USE
Genital herpes infection
Initial genital herpes infections in adults: Acyclovir 200 mg 5 times a day every 4 hours, for 5-10 days. Children under 2 years: 1/2 adult dose. For patients with "immunocompromised" or abnormal absorption in the intestine the dosage can be increased to 400 mg, or alternatively given treatment intravenously. Treatment should be started as early as possible, for recurrence, preferably in the period beginning with the first lesion.
Treatment of suppression of recurrent genital herpes infections: Acyclovir 400 mg 2 times a day or 200 mg 2-5 times a day, for 12 months.
Intermittent treatment of recurrent genital herpes infections: Acyclovir 200 mg 5 times a day every 4 hours, for 5 days.
Shingles and varicella infections
Adults: Acyclovir 800 mg 5 times a day every 4 hours, for 7-10 days.
Children 2 - 12 years: Acyclovir 400 - 800 mg 4 times a day, for 5 times.
Children under 2 years: Acyclovir 200 mg or 20 mg / kg BB 4 times a day, for 5 days.
Treatment must begin as early as possible and at the onset of symptoms of infection.
Patients who experience kidney function disorders need dose adjustments.
Some sufferers may experience a "break through" infection with a total dose of 800 mg a day. Treatment should be stopped periodically at intervals of 6 - 12 months with a view to observing possible changes in history.
SIDE EFFECTS
Side effects of Acyclovir that can occur: skin ulcers and digestive disorders such as nausea, vomiting, diarrhea and abdominal pain.
WARNING AND CAUTION
Acyclovir should not be used during pregnancy unless the benefits obtained far outweigh the risks to both the mother and the fetus.
Beware of giving to women who are breastfeeding.
DRUG INTERACTIONS
Probenecid increases the half-life and aciclovir AUC.
PACKAGING
Acyclovir 200 mg, tablet, box, fill 10 strips @ 10 capsules.
Acyclovir 400 mg, tablet, box, fill 10 strips @ 10 capsules.
